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Mo Li Lab

PUBLICATIONS:

 

1. Yue, W., Li, X., Zhan, X., Wang, L., Ma, J., Bi, M., Wang, Q., Gu, X., Xie, B., Liu, T., Guo, H., Zhu, X., Song, C., Qiao, J., Li M.*. PARP inhibitors suppress tumours via centrosome error-induced senescence independent of DNA damage response. EBioMedicine, 103. DOI: 10.1016/j.ebiom.2024.105129 (2024)

 

2. Jiang, Y., Yue, W., Bi, M., Guo, Y., Gu, X., Li M.*. Protocol for identifying metabolite biomarkers in patient uterine fluid for early ovarian cancer detection. STAR protocols, 5, 102953. DOI: 10.1016/j.xpro.2024.102953 (2024)

 

3. Xie, B., Zhang, M., Li, J., Cui, J., Zhang, P., Liu, F., Wu, Y., Deng, W., Ma, J., Li, X., Pan, B., Zhang, B., Zhang, H., Luo, A., Xu, Y., Li, M.* & Pu, Y.*. KAT8-catalyzed lactylation promotes eEF1A2-mediated protein synthesis and colorectal carcinogenesis. PNAS, 121,  e2314128121. DOI: 10.1073/pnas.2314128121 (2024)

 

4. Wang P., Ma J., Li W., Wang Q., Xiao Y., Jiang Y., Gu X., Wu Y., Dong S., Guo H.*, Li M.*. Profiling the metabolome of uterine fluid for early detection of ovarian cancer. Cell Rep Med,  DOI: 10.1016/j.xcrm.2023.101061 (2023)

 

5. Xie B., Pu Y., Yang F., Chen W., Yue W., Ma J., Zhang N., Jiang Y., Wu J., Lin Y., Liang X., Wang C., Zou P., Li M.*. Proteomic mapping and targeting of mitotic pericentriolar material in tumors bearing centrosome amplification. Cancer Res, 82:1736-1752. DOI: 10.1158/0008-5472.CAN-22-0225 (2022)

 

6. Xiao Y., Bi M., Guo H.,  Li M.*. Multi-omics approaches for biomarker discovery in early ovarian cancer diagnosis. EBioMedicine, 79, 104001. DOI: 10.1016/j.ebiom.2022.104001 (2022)

 

7. Li W., Gu X., Liu C., Shi Y., Wang P., Zhang N., Wu R., Leng L., Xie B., Song C., Li M.*. A synergetic effect of BARD1 mutations on tumorigenesis. Nat Commun, 12:1243. DOI:10.1038/s41467-021-21519-3 (2021)

 

8. Du H., Xia H., Liu T., Li Y.,Liu J., Xie B., Chen J., Liu T., Cao L., Liu S., Li S., Wang P., Wang D., Zhang Z., Li Y., Guo X., Wu A.*, Li M.* & You F.*. Suppression of ELF4 in ulcerative colitis predisposes host to colorectal cancer. iScience, 24:3. DOI:10.1016/j.isci.2021.102169 (2021)

 

9. Song J., Zhuang Y., Zhu C., Meng H., Lu B., Xie B., Peng J., Li M.*. & Yi C.*. Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation. Nat Chem Biol, 16:160-169. DOI: 10.1038/s41589-019-0420-5 (2020)

 

10. Ling X., Xie B., Gao X., Chang L., Zheng W., Chen H., Huang Y., Tan L., Li M.*. & Liu T.*. Improving the efficiency of precise genome editing with site-specific Cas9-oligonucleotide conjugates. Science Adv, 6:eaaz0051. DOI: 10.1126/sciadv.aaz0051 (2020)

 

11. Yang M., Jin Y., Fan S., Liang X., Jia J., Tan Z., Huang T., Li Y.*, Ma T.* & Li M.*. Inhibition of neddylation causes meiotic arrest in mouse oocyte. Cell Cycle, 18:1254-1267. DOI: 10.1080/15384101.2019.1617453 (2019)

 

12. Sun S., Osterman M. D. & Li M.*. Tissue specificity of DNA damage response and tumorigenesis. Cancer Biol Med,16:396-414. DOI: 10.20892/j.issn.2095-3941.2019.0097 (2019)

 

13. Miao Y., Wang P., Xie B., Yang M., Li S., Cui Z., Fan Y*., Li M.*. & Xiong B*. BRCA2 deficiency is a potential driver for human primary ovarian insufficiency. Cell Death Dis, 10:474. DOI: 10.1038/s41419-019-1720-0 (2019)

 

14. Jin Y., Yang M., Gao C., Yue W., Liang X., Xie B., Zhu X., Fan S., Li R. & Li M.*. Fbxo30 regulates chromosome segregation of oocyte meiosis. Cell Mol Life Sci, 76:2217-2229. DOI: 10.1007/s00018-019-03038-z (2019)

 

15. Xie B., Zhang L., Zhao H., Bai Q., Fan Y., Zhu X., Yu Y., Li R., Liang X., Sun Q. Y., Li M.*. & Qiao J*. Poly(ADP-ribose) mediates asymmetric division of mouse oocyte. Cell Res, 28:462-475. DOI: 10.1038/s41422-018-0009-7 (2018)

 

16. Li M., Chen Q. & Yu X. Chemopreventive Effects of ROS Targeting in a Murine Model of BRCA1-Deficient Breast Cancer. Cancer Research, 77:448-458. DOI: 10.1158/0008-5472.CAN-16-2350 (2017)

 

17. Li M., Chen Q., Ma T. & Yu X. Targeting reactive nitrogen species suppresses hereditary pancreatic cancer. Proc Natl Acad Sci USA, 114:7106-7111. DOI: 10.1073/pnas.1702156114 (2017)

 

18. Zhao H. C., Ding T., Ren Y., Li T. J., Li R., Fan Y., Yan J., Zhao Y., Li M., Yu Y*. & Qiao J*. Role of Sirt3 in mitochondrial biogenesis and developmental competence of human in vitro matured oocytes. Hum Reprod, 31:607-622. DOI: 10.1093/humrep/dev345 (2016)

 

19. Jin Y., Xu X., Wang X., Kuang H., Osterman M., Feng S., Han D., Wu Y., Li M.*. & Guo H.*. Increasing sensitivity to DNA damage is a potential driver for human ovarian cancer. Oncotarget, 7:49710-49721. DOI: 10.18632/oncotarget.10436 (2016)

 

20. Li M. & Yu X. The role of poly(ADP-ribosyl)ation in DNA damage response and cancer chemotherapy. Oncogene, 34:3349-3356. DOI: 10.1038/onc.2014.295 (2015)

 

21. Cao X. & Li M.*. A New Pathway for Senescence Regulation. Genomics Proteomics Bioinformatics, 13:333-335. DOI: 10.1016/j.gpb.2015.11.002 (2015)

 

22. Osterman M., Kathawa D., Liu D., Guo H., Zhang C., Li M.*, Yu X*. & Li F*. Elevated DNA damage response in pancreatic cancer. Histochem Cell Biol, 142:713-720. DOI: 10.1007/s00418-014-1245-7 (2014)

 

23. Li M., Bian C. & Yu X. Poly(ADP-ribosyl)ation is recognized by ECT2 during mitosis. Cell Cycle, 13:2944-2951. DOI: 10.4161/15384101.2014.947197 (2014)

 

24. Qiao J. & Li M. Getting the broken blastomere out of development. Cell Cycle, 12:3247-3248. DOI: 10.4161/cc.26636 (2013)

 

25. Li M. & Yu X. Function of BRCA1 in the DNA damage response is mediated by ADP-ribosylation. Cancer Cell, 23:693-704. DOI: 10.1016/j.ccr.2013.03.025 (2013)

 

26. Li M., Lu L. Y., Yang C. Y., Wang S. & Yu X. The FHA and BRCT domains recognize ADP-ribosylation during DNA damage response. Genes Dev, 27:1752-1768. DOI: 10.1101/gad.226357.113 (2013)